The vaccine proved safe Mesothelioma


According to a study recently conducted by a cancer research laboratory in the Netherlands, the latest new vaccine for mesothelioma to prevent and treat mesothelioma, a form of cancer that comes from exposure to asbestos. Researchers have tested the vaccine on 10 patients who had been diagnosed with mesothelioma, with all of them showed increased levels of antibodies against the disease and three of them showed that the tumor had decreased in size.

What are the symptoms of mesothelioma cancer?
The study, published in the American Journal of Respiratory and Critical Care Medicine, explains how vaccines work by creating dendritic cells tumor antigens in malignant mesothelioma in the lining fluid in the lungs of patients. Dr Joachim Aerts, the author of the study and lung specialist at the Erasmus Medical Center in Rotterdam, said that approach by using the patient's immune system to attack tumors and is useful for creating immunity to the disease, compared with conventional radiation or chemotherapy treatments.
How histological mesothelioma?


Dr. Aerts said that this is one of a relatively new form of treatment for cancer called immunotherapy. Mesothelioma vaccine can be used and relatively safer, with fewer side effects than current treatment methods. He expressed the hope that further studies can improve the survival rate of patients with mesotheliomas disease. Currently, patients diagnosed with mesothelioma, the prognosis of his life just to stay less than two years.


Patients who have been exposed to asbestos typically do not show symptoms of mesothelioma for several years, or even decades, after the initial exposure period. At the time, metastases of mesothelioma will continue to run in the lungs and seep into other organs. Another aspect of this study is that the vaccine could be a direct treatment for workers exposed to asbestos.


Although the side effects exhibited by patients in this study was not as severe as that experienced by patients undergoing chemotherapy or radiation treatments, one of the potential effects derived from changes of the immune system of patients during immunotherapy. The study noted that patients recover quickly and showed no signs of autoimmune disease related.


The distinction between pleural mesothelioma and peritoneal mesothelioma
Dr. Aerts noted a potential problem on immunosuppressive disorders. He said that the main problem for the treatment of mesothelioma is a tumor to create an environment in pleural mesothelium which can reduce the effects of the vaccine. He mentioned that the next step in vaccine development is how to provide immunosuppressive around the cancer to improve the effectiveness of treatment.


Dr. Aerts and his fellow researchers have done some tests on the effects on dendritic cells and how they may affect cancer tumors in mice. Previous research indicates that vaccination produces antibodies needed to destroy malignant cells and keep the healthy tissue around it to produce specific immunity.











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